Drug-Eluting Stents: Advanced Applications for the by Christopher J. White PDF

By Christopher J. White

ISBN-10: 0203301196

ISBN-13: 9780203301197

ISBN-10: 1842143034

ISBN-13: 9781842143032

The remedy for restenosis has been the Holy Grail of interventional cardiology because the introduction of coronary angioplasty within the past due Seventies. the advance of stents enhanced the sturdiness of angioplasty, yet in-stent restenosis used to be a tremendous challenge for sufferers and the physicians. To bring medications in the community on stents that hinder restenosis is a progressive enhance. Percutaneous revascularization know-how has leaped ahead, dramatically changing medical practices, with what could be the unmarried most vital improve within the heritage of cardiology. There are new supply structures and new medications presently being proven. regardless of the continued development, there has been a necessity to collate in one textual content, info on drug eluting stents for coronary sickness. Chris White and co-workers have prepare a logically equipped textual content that progresses from concept to perform, and addresses pharmacologic, technical and strategic matters as they relate to the location of coronary drug-eluting stents.

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Drug-Eluting Stents: Advanced Applications for the - download pdf or read online

The therapy for restenosis has been the Holy Grail of interventional cardiology because the introduction of coronary angioplasty within the overdue Seventies. the improvement of stents more desirable the sturdiness of angioplasty, yet in-stent restenosis used to be a big challenge for sufferers and the physicians. To convey medicines in the community on stents that hinder restenosis is a innovative enhance.

Additional resources for Drug-Eluting Stents: Advanced Applications for the Management of Coronary Disease

Sample text

Vrolix MC, Legrand VM, Reiber JH et al. Heparin-coated Wiktor stents in human coronary arteries (MENTOR trial). MENTOR Trial Investigators. Am J Cardiol 2000; 86: 385–89 22. Wohrle J, Al-Khayer E, Grotzinger U et al. Comparison of the heparin coated vs the uncoated JOSTENT® – no influence on restenosis or clinical outcome. Eur Heart J 2001; 22: 1808–16 23. Sousa JE, Serruys PW, Costa MA. New frontiers in cardiology: drug-eluting stents. Part I. Circulation 2003; 107: 2274–79 24. Klugherz BD, Llanos G, Lieuallen W et al.

Waksman R, Ajani A, Pichard AD et al. Oral rapamycin to inhibit restenosis after stenting of de-novo coronary lesions. The Oral Rapamune to Inhibit Restenosis (ORBIT) study. J Am Coll Cardiol 2004; 44: 1386–92 25. Rodriguez AE, Rodriguez-Alemparte M, Fernandez-Pereira C et al. Oral rapamycin in patients undergoing coronary stent therapy: final results of the ORAR study (Oral Rapamycin in Argentina). J Am Coll Cardiol 2004; 43: 102A 26. Brara PS, Moussavian M, Grise MA et al. Pilot trial of oral rapamycin for recalcitrant restenosis.

The results of the clinical studies using non-polymer-based paclitaxel delivery have been inconclusive. Cook has sponsored three clinical trials that involved non-polymer-based stents. 7 µg/mm2) with a proprietary method, and were compared with the bare metal stent. A dose-dependent effect of paclitaxel on intimal proliferation was reported, but the clinical events were not different at 1 year. 04 mm in the controls). 0 µg/mm2) (Alan Heldman MD, Johns Hopkins University, unpublished data, 2002).

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Drug-Eluting Stents: Advanced Applications for the Management of Coronary Disease by Christopher J. White


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