Download PDF by Philip N Patsalos: Antiepileptic Drug Interactions: A Clinical Guide

By Philip N Patsalos

ISBN-10: 1447124332

ISBN-13: 9781447124337

ISBN-10: 1447124340

ISBN-13: 9781447124344

Antiepileptic Drug Interactions: A scientific advisor, moment Edition presents a pocket-sized, systematic description of the main clinically suitable drug interactions that happen among AEDs and likewise among AEDs and non-AEDs. AEDs are provided alphabetically and by way of drug category in 3 sections for simple entry: Drug interactions among AEDs; Drug interactions among AEDs and non-AEDs: Interactions affecting AEDs; and Drug interactions among AEDs and non-AEDs: Interactions tormented by AEDs.

Antiepileptic Drug Interactions: A medical advisor, moment Edition might be useful physicians make extra rational offerings while polytherapy regimens are indicated and will be of curiosity to all who deal with sufferers with epilepsy: neurologists and neurosurgeons, trainees in any respect degrees, basic practitioners and epilepsy nurse specialists.

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Additional resources for Antiepileptic Drug Interactions: A Clinical Guide

Example text

Bupropion . . . . . . . . . . . . . . . . . . Dextromethorphan . . . . . . . . . . . . . . Dihydroergotamine . . . . . . . . . . . . . . Fexofenadine . . . . . . . . . . . . . . . . . Flunarizine . . . . . . . . . . . . . . . . . . Glibenclamide (Glyburide) . . . . . . . . . . . Isoxicam . . . . . . . . . . . . . . . . . . . Lidocaine (Lignocaine) . . . . . . . . . . .

Ziprasidone . . . . . . . . . . . . . . . Benzodiazepines . . . . . . . . . . . . . . . Alprazolam. . . . . . . . . . . . . . . Clobazam . . . . . . . . . . . . . . . . Clonazepam . . . . . . . . . . . . . . . Diazepam . . . . . . . . . . . . . . . . Lorazepam . . . . . . . . . . . . . . . Midazolam . . . . . . . . . . . . . . . Lithium. . . . . . . . . . .

The smaller the difference between toxicity and efficacy, the greater the likelihood that a drug interaction will have serious clinical consequences. Prevention of AED interactions is best achieved by avoiding unnecessary polytherapy or by selecting alternative agents that have less potential to interact. The management of interactions begins with anticipating their occurrence and being familiar with the mechanisms involved (Fig. 1). Indeed, awareness of the mechanism of a drug interaction can be used to clinical advantage.

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Antiepileptic Drug Interactions: A Clinical Guide by Philip N Patsalos


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